ATF4 over-expression increased IgG1 productivity in Chinese hamster ovary cells
نویسندگان
چکیده
منابع مشابه
ATF4 over-expression increased IgG1 productivity in Chinese hamster ovary cells
Introduction The endoplasmic reticulum (ER) is the major organelle of synthesis of protein and forms a membranous network throughout the cell. According to Shimizu and Hendershot [1], about one third of the total proteins produced are synthesized in the ER. The ER lumen possesses a unique environment for high quality control for protein folding and assembly. It contains high concentrations of m...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s8-o11